石慧，女，医学博士，博士后合作导师，硕士研究生导师，广东医科大学高层次人才。东莞市中医药防治消化道疑难病证重点实验室骨干成员；国家中药现代化工程技术研究中心东莞分中心秘书长。博士毕业于暨南大学，暨南大学中西医结合博士后。以第一作者/共同第一作者/通讯作者身份发表在Int. J. Biol. Macromol. (IF: 8.2), J. Exp. Clin. Canc. Res. (IF: 11.3), Food. Funct. (IF: 6.317)等学术期刊发表SCI论文10余篇，申请发明专利3项。主持国家级项目1项、省市级项目1项。

研究方向：

中药和天然药物活性大分子（蛋白、多肽、多糖）结构及其防治消化道疑难病证作用机制研究。

近三年的5篇代表性论文：

(1)Hui Shi; Santosh Panjikar; Chunlei Li; Xiaozheng Ou; Yun Zhou; Kunhao Zhang; Liyan Song; Rongmin Yu; Lianli Sun; Jianhua Zhu. Characterization of a novel recombinant calcium-binding protein from Arca subcrenata and its anti-hepatoma activities in vitro and in vivo, Int. J. Biol. Macromol., 2023, 245: 125513. PMID: 37353116.

(2)Hui Shi; Jianhuan Li; Fei Liu; Sixue Bi; Weijuan Huang; Yuanyuan Luo; Man Zhang; Liyan Song; Rongmin Yu; Jianhua Zhu. Characterization of a novel polysaccharide from Arca subcrenata and its immunoregulatory activities in vitro and in vivo, Food Funct., 2023, 14: 822-835. PMID: 36622059.

(3)Weijuan Huang *; Songbin Guo *; Hui Shi *; Xinling Li *; Yong Zhu *; Mei Li; Liyan Song; Rongmin Yu; Qingqing Cai; Xiaopeng Tian. The β-catenin-LINC00183-miR-371b-5p-Smad2/LEF1 axis promotes adult T-cell lymphoblastic lymphoma progression and chemoresistance, J. Exp. Clin. Canc. Res., 2023, 42: 105. PMID: 37106379.

(4)Hui Shi; Sixue Bi; Hang Li; Jianhuan Li; Chunlei Li; Rongmin Yu; Liyan Song; Jianhua Zhu. Purification and characterization of a novel mixed-linkage α,β-D glucan from Arca subcrenata and its immunoregulatory activity, Int. J. Biol. Macromol., 2021, 182: 207-216. PMID: 33831453.

(5) Hui Shi; Xuqiao Hu; Hang Zheng; Chunlei Li; Lianli Sun; Zhongyi Guo; Weijuan Huang; Rongmin Yu; Liyan Song; Jianhua Zhu. Two novel antioxidant peptides derived from Arca subcrenata against oxidative stress and extend lifespan in Caenorhabditis elegans, J. Funct. Foods, 2021, 81: 104462.

主持的科研项目:

（1）国家自然科学基金（30万元，82204583，2023.1-2025.12）

（2）广东省自然科学基金-面上项目（10万元，2023A1515012077，2023.1-2025.12）

邮箱：shih2024@gdmu.edu.cn；sh613050@163.com